Start

Serum sodium level decreases (water excess)

Serum sodium level increases (water deficit)

Serum osmolality normolizes.

End

Serum osmolality rises to more than 300 mOsm/kg.

Serum osmolality falls to less than 280 mOsm/kg.

Thirst increases, leading to increased water intake.

Thirst diminishes, leading to decreased water intake.

ADH release is suppressed.

ADH release increases.

Renal water excretion increases.

Renal water excretion diminishes.