What Happens in SIADH
What Happens in SIADH - Flowchart What Happens in SIADH What Happens in SIADH
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Body secretes too much ADH.

Body secretes too much ADH.

Body secretes too much ADH.

End

End

End

These factors lead to increased sodium excretion and a shifting of fluid into cells.

These factors lead to increased sodium excretion and a shifting of fluid into cells.

These factors lead to increased sodium excretion and a shifting of fluid into cells.

ADH increases the permeability of renal tubules.

ADH increases the permeability of renal tubules.

ADH increases the permeability of renal tubules.

Increased permeability of renal tubules increases water retention and extracellular fluid volume.

Increased permeability of renal tubules increases water retention and extracellular fluid volume.

Increased permeability of renal tubules increases water retention and extracellular fluid volume.

Increased extracellular fluid volume leads to:

Increased extracellular fluid volume leads to:

Increased extracellular fluid volume leads to:

Reduced plasma osmolality

Reduced plasma osmolality

Reduced plasma osmolality

Dilutional hyponatremia

Dilutional hyponatremia

Dilutional hyponatremia

Diminished aldosterone secretion

Diminished aldosterone secretion

Diminished aldosterone secretion

Elevated glomerular filtration rate

Elevated glomerular filtration rate

Elevated glomerular filtration rate

Patient develops thirst,dyspnea on exertion, vomiting, abdominal cramps, confusion, lethargy, and hyponatremia.

Patient develops thirst,dyspnea on exertion, vomiting, abdominal cramps, confusion, lethargy, and hyponatremia.

Patient develops thirst,dyspnea on exertion, vomiting, abdominal cramps, confusion, lethargy, and hyponatremia.