Lung(Pathological) - TNM Calc
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Primary Tumor (T)
Regional Lymph Nodes (N)
Distant Metastasis (M)
R e s u l t s
Stage
 
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Lung(Pathological) - TNM Calc

This view displays the TNM formula.Please select appropriate value from the list for T/N/M variables. The result will be displayed, based on your selection of variables.

Pathological T (pT)

pT Category pT Criteria
pTX Primary tumor cannot be assessed, or tumor proven by the presence of malignant cells in sputum or bronchial washings but not visualized by imaging or bronchoscopy
pT0 No evidence of primary tumor
pTis Carcinoma in situ; Squamous cell carcinoma in situ (SCIS); Adenocarcinoma in situ (AIS): adenocarcinoma with pure lepidic pattern, less than or equal to 3 cm in greatest dimension
pT1 Tumor less than or equal to 3 cm in greatest dimension, surrounded by lung or visceral pleura, without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus)
pT1mi Minimally invasive adenocarcinoma: adenocarcinoma (less than or equal to 3 cm in greatest dimension) with a predominantly lepidic pattern and less than or equal to 5 mm invasion in greatest dimension
pT1a Tumor less than or equal to 1 cm in greatest dimension. A superficial, spreading tumor of any size whose invasive component is limited to the bronchial wall and may extend proximal to the main bronchus also is classified as T1a, but these tumors are uncommon.
pT1b Tumor greater than 1 cm but less than or equal to 2 cm in greatest dimension
pT1c Tumor greater than 2 cm but less than or equal to 3 cm in greatest dimension
pT2 Tumor greater than 3 cm but less than or equal to 5 cm or having any of the following features: Involves the main bronchus regardless of distance to the carina, but without involvement of the carina; Invades visceral pleura (PL1 or PL2); Associated with atelectasis or obstructive pneumonitis that extends to the hilar region, involving part or all of the lung. T2 tumors with these features are classified as T2a if less than or equal to 4 cm or if the size cannot be determined and T2b if greater than 4 cm but less than or equal to 5 cm.
pT2a Tumor greater than 3 cm but less than or equal to 4 cm in greatest dimension
pT2b Tumor greater than 4 cm but less than or equal to 5 cm in greatest dimension
pT3 Tumor greater than 5 cm but less than or equal to 7 cm in greatest dimension or directly invading any of the following: parietal pleura (PL3), chest wall (including superior sulcus tumors), phrenic nerve, parietal pericardium; or separate tumor nodule(s) in the same lobe as the primary
pT4 Tumor greater than 7 cm or tumor of any size invading one or more of the following: diaphragm, mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, or carina; separate tumor nodule(s) in an ipsilateral lobe different from that of the primary
cTX Primary tumor cannot be assessed, or tumor proven by the presence of malignant cells in sputum or bronchial washings but not visualized by imaging or bronchoscopy
cT0 No evidence of primary tumor
cTis Carcinoma in situ; Squamous cell carcinoma in situ (SCIS); Adenocarcinoma in situ (AIS): adenocarcinoma with pure lepidic pattern, less than or equal to 3 cm in greatest dimension
cT1 Tumor less than or equal to 3 cm in greatest dimension, surrounded by lung or visceral pleura, without bronchoscopic evidence of invasion more proximal than the lobar bronchus (i.e., not in the main bronchus)
cT1mi Minimally invasive adenocarcinoma: adenocarcinoma (less than or equal to 3 cm in greatest dimension) with a predominantly lepidic pattern and less than or equal to 5 mm invasion in greatest dimension
cT1a Tumor less than or equal to 1 cm in greatest dimension. A superficial, spreading tumor of any size whose invasive component is limited to the bronchial wall and may extend proximal to the main bronchus also is classified as T1a, but these tumors are uncommon.
cT1b Tumor greater than 1 cm but less than or equal to 2 cm in greatest dimension
cT1c Tumor greater than 2 cm but less than or equal to 3 cm in greatest dimension
cT2 Tumor greater than 3 cm but less than or equal to 5 cm or having any of the following features: Involves the main bronchus regardless of distance to the carina, but without involvement of the carina; Invades visceral pleura (PL1 or PL2); Associated with atelectasis or obstructive pneumonitis that extends to the hilar region, involving part or all of the lung. T2 tumors with these features are classified as T2a if less than or equal to 4 cm or if the size cannot be determined and T2b if greater than 4 cm but less than or equal to 5 cm.
cT2a Tumor greater than 3 cm but less than or equal to 4 cm in greatest dimension
cT2b Tumor greater than 4 cm but less than or equal to 5 cm in greatest dimension
cT3 Tumor greater than 5 cm but less than or equal to 7 cm in greatest dimension or directly invading any of the following: parietal pleura (PL3), chest wall (including superior sulcus tumors), phrenic nerve, parietal pericardium; or separate tumor nodule(s) in the same lobe as the primary
cT4 Tumor greater than 7 cm or tumor of any size invading one or more of the following: diaphragm, mediastinum, heart, great vessels, trachea, recurrent laryngeal nerve, esophagus, vertebral body, or carina; separate tumor nodule(s) in an ipsilateral lobe different from that of the primary
Pathological N (pN)
pN Category pN Criteria
pNX Regional lymph nodes cannot be assessed
pN0 No regional lymph node metastasis
pN1 Metastasis in ipsilateral peribronchial and /or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension
pN2 Metastasis in ipsilateral mediastinal and /or subcarinal lymph node(s)
pN3 Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s)
cNX Regional lymph nodes cannot be assessed
cN0 No regional lymph node metastasis
cN1 Metastasis in ipsilateral peribronchial and /or ipsilateral hilar lymph nodes and intrapulmonary nodes, including involvement by direct extension
cN2 Metastasis in ipsilateral mediastinal and /or subcarinal lymph node(s)
cN3 Metastasis in contralateral mediastinal, contralateral hilar, ipsilateral or contralateral scalene, or supraclavicular lymph node(s)

Definition of Distant Metastasis (M)- Pathological M (pN)

pM Category pM Criteria
cM0 No distant metastasis
cM1 Distant metastasis
cM1a Separate tumor nodule(s) in a contralateral lobe; tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion. Most pleural (pericardial) effusions with lung cancer are a result of the tumor. In a few patients, however, multiple microscopic examinations of pleural (pericardial) fluid are negative for tumor, and the fluid is nonbloody and not an exudate. If these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging descriptor.
cM1b Single extrathoracic metastasis in a single organ (including involvement of a single nonregional node)
cM1c Multiple extrathoracic metastases in a single organ or in multiple organs
pM1 Distant metastasis, microscopically confirmed
pM1a Separate tumor nodule(s) in a contralateral lobe; tumor with pleural or pericardial nodules or malignant pleural or pericardial effusion, microscopically confirmed. Most pleural (pericardial) effusions with lung cancer are a result of the tumor. In a few patients, however, multiple microscopic examinations of pleural (pericardial) fluid are negative for tumor, and the fluid is nonbloody and not an exudate. If these elements and clinical judgment dictate that the effusion is not related to the tumor, the effusion should be excluded as a staging descriptor.
pM1b Single extrathoracic metastasis in a single organ (including involvement of a single nonregional node), microscopically confirmed
pM1c Multiple extrathoracic metastases in a single organ or in multiple organs, microscopically confirmed