Esophagus and Esophagogastric Junction - Adenocarcinoma (Pathological) - TNM Calc
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Primary Tumor (T)
Regional Lymph Nodes (N)
Distant Metastasis (M)
Histologic Grade (G)
R e s u l t s
Stage
 
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Esophagus and Esophagogastric Junction - Adenocarcinoma (Pathological) - TNM Calc

This view displays the TNM formula. Please select appropriate value from the list for T/N/M/G variables. The result will be displayed, based on your selection of variables.

Definition of Primary Tumor (T)

T Category T Criteria
TX Tumor cannot be assessed
T0 No evidence of primary tumor
Tis High-grade dysplasia, defined as malignant cells confined to the epithelium by the basement membrane
T1 Tumor invades the lamina propria, muscularis mucosae, or submucosa
T1a Tumor invades the lamina propria or muscularis mucosae
T1b Tumor invades the submucosa
T2 Tumor invades the muscularis propria
T3 Tumor invades adventitia
T4 Tumor invades adjacent structures
T4a Tumor invades the pleura, pericardium, azygos vein, diaphragm, or peritoneum
T4b Tumor invades other adjacent structures, such as the aorta, vertebral body, or airway

Definition of Regional Lymph Node (N)

N Category N Criteria
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis in one or two regional lymph nodes
N2 Metastasis in three to six regional lymph nodes
N3 Metastasis in seven or more regional lymph nodes

Definition of Distant Metastasis (M)

M Category M Criteria
M0 No distant metastasis
M1 Distant metastasis

Definition of Grade (G)

G G Definition
GX Grade cannot be assessed
G1 Well-differentiated adenocarcinoma. In these tumors, greater than 95% of the tumor is composed of well-formed glands.
G2 Moderately differentiated adenocarcinoma. In these tumors, 50-95% of the tumor shows gland formation. Most adenocarcinomas are categorized as moderately differentiated tumors.
G3 Poorly differentiated adenocarcinoma. These tumors are composed predominantly of nests and sheets of neoplastic cells. Only less than 50% of the tumor shows gland formation.
NA Not Applicable