Poisoning & Drug Overdose provides practical advice for the diagnosis and management of poisoning and drug overdose and concise information about common industrial chemicals.
The manual is divided into four sections and an index, each identifiied by a black tab in the right margin. Section I leads the reader through initial emergency management, including treatment of coma, hypotension, and other common complications; physical and laboratory diagnosis; and methods of decontamination and enhanced elimination of poisons. Section II provides detailed information for common drugs and poisons. Section III describes the use and side effects of antidotes and therapeutic drugs. Section IV describes the medical management of chemical spills and occupational chemical exposures and includes a table of over 500 chemicals. The Index is comprehensive and extensively cross-referenced.
The manual is designed to allow the reader to move quickly from section to section, obtaining the needed information from each. For example, in managing a patient with isoniazid intoxication, the reader will fiind specifiic information about isoniazid toxicity in Section II, practical advice for gut decontamination and management of complications such as seizures in Section I, and detailed information about dosing and side effects for the antidote pyridoxine in Section III.
ACKNOWLEDGMENTS
The success of the first and second editions of this manual would not have been pos-sible without the combined efforts of the staff, faculty, and fellows of the San Francisco Bay Area Regional Poison Control Center, to whom we are deeply indebted. From its inception, this book has been a project by and for our poison center; as a result, all royalties from its sale have gone to our center’s operating fund and not to any individual editor or author.
In January 1997, four independent poison control centers joined their talents to become the California Poison Control System, administered by the University of California, San Francisco. With the subsequent editions, the manual became a project of our statewide system, bringing in new authors and editors.
On behalf of the authors and editors of the eighth edition, our sincere thanks go to all those who contributed to one or more of the fiirst seven editions:
Suad Abdullah Saif Al Abri, MD
Timothy E. Albertson, MD, PhD
Judith A. Alsop, PharmD
Ilene Brewer Anderson, PharmD
Ann Arens, MD
Patil Armenian, MD
Margaret Atterbury, MD
Georgeanne M. Backman
John Balmes, MD
Shireen Banerji, PharmD
James David Barry, MD
Charles E. Becker, MD
Neal L. Benowitz, MD
Bruce Bernard, MD
David P. Betten, MD
Kathleen Birnbaum, PharmD
Paul D. Blanc, MD, MSPH
Stephen Born, MD
Christopher R. Brown, MD
Randall G. Browning, MD, MPH
James F. Buchanan, PharmD
Alan Buchwald, MD
Cindy Burkhardt, PharmD
Chris Camillieri, DO
F. Lee Cantrell, PharmD
Terry Carlson, PharmD
Shaun D. Carstairs, MD
Gregory Cham, MD
Chulathida Chomchai, MD
Summon Chomchai, MD
Richard F. Clark, MD
Matthew D. Cook, MD
G. Patrick Daubert, MD
Delia Dempsey, MD
Charlene Doss
Chris Dutra, MD
Jo Ellen Dyer, PharmD
Brent R. Ekins, PharmD
Andrew Erdman, MD
Gary Everson, PharmD
Jeffrey Fay, PharmD
Thomas J. Ferguson, MD, PhD
Donna E. Foliart, MD, MPH
Frederick Fung, MD
Nasim Ghafouri, PharmD
Mark J. Galbo, MS
Fabian Garza, PharmD
Richard J. Geller, MD, MPH
Robert L. Goldberg, MD
Joanna Goralka, PharmD
Colin S. Goto, MD
Gail M. Gullickson, MD
Christine A. Haller, MD
Jennifer Hannum, MD
Sandra Hayashi, PharmD
Patricia H. Hiatt, BS
Raymond Ho, PharmD
B. Zane Horowitz, MD
Yao-min Hung, MD
David L. Irons, PharmD
Leslie M. Israel, DO, MPH
Sam Jackson, MD, MBA
Thanjira Jiranankatan, MD
Gerald Joe, PharmD
Jeffrey R. Jones, MPH, CIH
Paul A. Khasigian, PharmD
Thomas E. Kearney, PharmD
Kathryn H. Keller, PharmD
Michael T. Kelley, MD
Susan Y. Kim-Katz, PharmD
Lada Kokan, MD
Michael J. Kosnett, MD
Allyson Kreshak, MD
Amy Kunihiro, MD
Grant D. Lackey, PharmD
Chi-Leung Lai, PharmD
Rita Lam, PharmD
Shelly Lam, PharmD
John P. Lamb, PharmD
Belle L. Lee, PharmD
Darren H. Lew, PharmD
Diane Liu, MD, MPH
Jon Lorett, PharmD
Derrick Lung, MD, MPH
Binh T. Ly, MD
Richard Lynton, MD
Conan MacDougall, PharmD
Tatiana M. Mamantov, MD
Beth H. Manning, PharmD
Anthony S. Manoguerra, PharmD
Kathy Marquardt, PharmD
Michael J. Matteucci, MD
Timothy D. McCarthy, PharmD
Howard E. McKinney, PharmD
Kathryn H. Meier, PharmD
Michael A. Miller, MD
Alicia Minns, MD
S. Todd Mitchell, MD
Eileen Morentz
Walter H. Mullen, PharmD
Stephen W. Munday, MD, MPH, MS
Nancy G. Murphy, MD
Frank J. Mycroft, PhD, MPH
Joshua Nogar, MD
Sean Patrick Nordt, MD, PharmD
Charles W. O'Connell, MD
Steve Offerman, MD
Kent R. Olson, MD
Michael O'Malley, MD, MPH
Gary Joseph Ordog, MD
John D. Osterloh, MD
Kelly P. Owen, MD
Gary Pasternak, MD
Manish Patel, MD
Paul D. Pearigen, MD
Joshua B. Radke
Cyrus Rangan, MD
Brett A. Roth, MD
Freda M. Rowley, PharmD
Thomas R. Sands, PharmD
Aaron Schnier, MD
Jay Schrader, CPhT
Kerry Schwarz, PharmD
Dennis J. Shusterman, MD, MPH
Craig Smollin, MD
Karl A. Sporer, MD
Jeffrey R. Suchard, MD
Mark E. Sutter, MD
Winnie W. Tai, PharmD
David A. Tanen, MD
S. Alan Tani, PharmD
John H. Tegzes, VMD
R. Steven Tharratt, MD
Josef G. Thundiyil, MD, MPH
Christian Tomaszewski, MD
Ben T. Tsutaoka, PharmD
Mary Tweig, MD
Janna H. Villano, MD
Rais Vohra, MD
Peter H. Wald, MD, MPH
Michael J. Walsh, PharmD
Jonathan Wasserberger, MD
Janet S. Weiss, MD
R. David West, PharmD
Timothy J. Wiegand, MD
Saralyn R. Williams, MD
Joyce Wong, PharmD
Olga F. Woo, PharmD
Alan H. B. Wu, PhD
Lisa Wu, MD
Evan T. Wythe, MD
Peter Yip, MD
Michael Young, DO
Shoshana Zevin, MD
We are also grateful for the numerous comments and suggestions received from colleagues, students, and the editorial staff at McGraw Hill, which helped us to improve the manual with each edition.
Kent R. Olson, MD
Craig G. Smollin, MD
San Francisco, California
April 2022