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Figure 1-5

The rabbit head-drop assay.

H. A. Halladay of Squibb pharmaceutical company developed a method of standardizing doses of curare and d-tubocurarine. A normal rabbit (A) had 0.1 mL of aqueous cecurane solution injected every 15 seconds until it could no longer raise its head (B).

H. A. Halladay of Squibb pharmaceutical company developed a method of standardizing doses of curare and d-tubocurarine. A normal rabbit (A) had 0.1 mL of aqueous cecurane solution injected every 15 seconds until it could no longer raise its head (B).