Adult Dosing
Duodenal ulcer
- Acute treatment: 150 mg PO bid. Alt: 300 mg PO qhs
- Maintenance dose: 150 mg PO qhs
Pathological hypersecretory conditions
- 150 mg PO bid, may incr. PO dose PRN
- Max: 6000 mg/day
Benign gastric ulcer
- Acute treatment: 150 mg PO bid
- Maintenance dose: 150 mg PO qhs
GERD
Erosive esophagitis
- Acute treatment: 150 mg PO qid
- Maintenance dose: 150 mg PO bid
Pediatric Dosing
Active duodenal/gastric ulcer
1 month-16 yrs
- Acute treatment: 2-4 mg/kg PO bid. Max: 300 mg/day
- Maintenance dose: 2-4 mg/kg PO qd. Max: 150 mg/day
Erosive esophagitis
- 1 month-16 yrs: 5-10 mg/kg/day PO divided bid
- Max: 600 mg/day
GERD
- 1 month-16 yrs: 5-10 mg/kg/day PO divided bid
- Max: 300 mg/day
[Outline]
Renal Dose Adjustment (Based on CrCl)
- Severe renal impairment CrCl <50 mL/min: 150 mg PO qd, may increase to 150 mg PO bid with extreme caution
Hepatic Dose Adjustment
- Hepatic impairment: Dose adjustments not defined. Caution advised
- Appropriately adjust dosage in patients with impaired renal function as ranitidine is excreted primarily by the kidney
- It may precipitate acute porphyric attacks in patients with acute porphyria. Avoid use in patients with a history of acute porphyria
- Symptomatic response to ranitidine therapy does not preclude the presence of gastric malignancy
Cautions: Use cautiously in
- Hepatic impairment
- Renal impairment
- Elderly or debilitated patients
- Chronic pulmonary disease
- Diabetes mellitus
- Immunocompromised
Pregnancy Category:B
Breastfeeding: Maternal ranitidine would not be expected to cause any adverse effects in breastfed infants. No special precautions are required. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 30 November 2010). According to manufacturer's data, ranitidine is excreted in human milk. Caution should be exercised when ranitidine is administered to a nursing mother.
US Trade Name(s)
- Zantac
- Zantac 25
- Zantac 75
- Zantac 150
- Zantac 300
US Availability
ranitidine (generic)
- TABS: 150, 300 mg
- OTC TABS: 75, 150 mg
- CAPS: 150, 300 mg
- SYRUP: 15 mg/mL
Zantac
Zantac 25
Zantac 75
Zantac 150
- TABS: 150 mg
- OTC TABS: 150 mg
Zantac 300
Canadian Trade Name(s)
- Acid Reducer
- Maximum Strength Acid Reducer
- Nu-Ranit
- Maximum Strength Acid Reducer Without Prescription
- Zantac
Canadian Availability
ranitidine (generic)
- TABS: 150, 300 mg
- OTC TABS: 75 mg
- SOLN: 15 mg/mL
Acid Reducer
Maximum Strength Acid Reducer
Maximum Strength Acid Reducer Without Prescription
Nu-Ranit
Zantac
- OTC TABS: 75 mg
- TABS: 150, 300 mg
- SOLN: 15 mg/mL
UK Trade Name(s)
- Zantac
- Zantac Syrup
- Zantac 75 Relief
- Zantac 75 Relief Dissolve
- Zantac Effervescent
UK Availability
ranitidine(generic)
- TABS: 150, 300 mg
- SOLN: 15 mg/mL
Zantac Syrup
Zantac
Zantac 75 Relief
Zantac 75 Relief Dissolve
Zantac Effervescent
- Effervescent TABS: 150, 300 mg
Australian Trade Name(s)
- Ausran
- Gavilast 12 Hour Action Tablets
- Hexal Ranitic Forte
- Hexal Ranitic
- Ranihexal
- Ranoxyl Heartburn Relief
- Ranoxyl
- Ultac
- Zantac Relief
- Zantac Relief Extra Strength
Australian Availability
ranitidine (generic)
Ausran, Rani 2, Ranihexal, Ulcaid
Gavilast 12 Hour Action Tablets, Hexal Ranitic, Ranoxyl, Ranoxyl Heartburn Relief, Ultac, Zantac Relief
Hexal Ranitic Forte, Zantac Relief Extra Strength
Zantac
- TABS: 150, 300 mg
- Effervescent TABS: 150 mg
- SYRUP: 150 mg/10 mL
[Outline]
Pricing data from www.DrugStore.com in U.S.A.
- Ranitidine HCl 300 MG CAPS [Bottle] (SANDOZ)
30 mg = $62.99
90 mg = $171.97 - Zantac 75 75 MG TABS [Box] (J & J HEALTHCARE/CONSUMER)
30 mg = $17.99
60 mg = $26.98 - Zantac 15 MG/ML SYRP [Bottle] (GLAXO SMITH KLINE)
300 ml = $224.99
900 ml = $656.97 - Zantac 300 MG TABS [Bottle] (GLAXO SMITH KLINE)
30 mg = $240.99
90 mg = $684.94 - Zantac 150 MG TABS [Bottle] (GLAXO SMITH KLINE)
60 mg = $259
180 mg = $743.95 - Ranitidine HCl 150 MG TABS [Bottle] (AMNEAL PHARMACEUTICALS)
90 mg = $17.99
180 mg = $25.97 - Ranitidine 75 75 MG TABS [Box] (MAJOR PHARMACEUTICALS)
30 mg = $13.99
60 mg = $16.97 - Zantac EFFERdose 25 MG TBEF [Box] (GLAXO SMITH KLINE)
60 mg = $241
180 mg = $705.95
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
