section name header

General Reference

(Jama 2000;284:350)
previously dermatitis or herpes gestationis

Signs and Symptoms

Si:Vesicles and bullae with onset any time during pregnancy; may flare at delivery

Course

Recurs in subsequent pregnancies

Complications

Premature delivery sometimes

Lab and Xray

Lab:

Path:Biopsy shows specific subepidermal vesicles with polys early, then eosinophiles; C3 deposition on epidermal basement membrane from low titer pemphigoid type IgG auto-antibodies

Treatment

Rx:Systemic steroids