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General Reference

Nejm 2003;348:447

Pathophys and Cause

Cause: Echinococcus granulosusand multilocularis(hydatid cyst); sometimes T. solium(see above)

Pathophys:Like a neoplasm, echinococcal cysts grow over years with appearance of secondary cysts

Epidemiology

Humans are only intermediate host, ie, do not spread eggs in stool, rather only have encysted organisms

Signs and Symptoms

Si:Mass effects anywhere

Lab and Xray

Lab:

CSF:in cysticercosis: aseptic picture with low sugar; eosinophils

Serol: IHA titers increased (from CDC) are pos in 90% with liver, 75% with lung involvement

Treatment

Rx:

Albendazole 5 mg/kg po tid × 28-56 d + either surgical or percutaneous drainage (Nejm 1997;337:881)

for T. soliumcysticercosis: surgical excision; albendazole as above or praziquantel + dexamethasone (Nejm 1984;311:1492); in cerebral cysticercosis, rx only w albendazole 800 mg + dexamthasone 6 mg po qd × 10 d, not seizure meds (Nejm 2004;350:249)