Adult Dosing

Acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus

• Instill 0.25 mL in affected ear(s) q12 hrs x 7 days

Pediatric Dosing

• Safety and effectiveness in pediatric patients <1 yr of age have not been established

Acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus

• Children >1 yr: Instill 0.25 mL in affected ear(s) q12 hrs x 7 days

[Outline]

• Adult Dosing
• Pediatric Dosing

• Acute otitis externa due to susceptible isolates of Pseudomonas aeruginosa or Staphylococcus aureus

• Hypersensitivity to any of the ingredients of the product

• N/A

Renal Dose adjustment

• Renal impairment: Dose adjustment information not available

Hepatic Dose adjustment

• Hepatic impairment: Dose adjustment information not available

• For otic use only
• Not for injection, inhalation or ophthalmic use
• Discontinue the drug if any rash or hypersensitivity occurs
• Discontinue the drug if overgrowth of nonsusceptible organisms, including yeast and fungi occur and use alternate therapy
• Perform cultures if the infection is not improved after one week of therapy, which may help guide further treatment

Cetraxal, Ciloxan interacts with :

	Abstral
	Actiq
	Alfenta
	Alfentanil
	Altropev
	Antacids
	Anticancer Doses
	Asenapine
	Atorvastatin
	Bellergal-S
	Cafergot
	Calcium Polycarbophil
	Carafate
	Carbamazepine
	Carbatrol
	Clozapine
	Clozaril
	Colchicine
	Colcrys
	D.H.E. 45
	Didanosine
	Dihydroergotamine
	Dolophine
	Duragesic
	Elixophyllin
	Epitol
	Equetro
	Ergomar
	Ergotamine
	Fazaclo ODT
	Fentanyl
	Fentora
	FiberCon
	Folotyn
	Iron
	Lazanda
	Lipitor
	Lovastatin
	Methadone
	Methadose
	Methotrexate
	Methysergide
	Mevacor
	Migranal
	Navelbine
	Olanzapine
	Oncovin
	Onsolis
	Orap
	Otrexup
	Oxecta
	Oxycodone
	Oxycontin
	OxyFast
	Percocet
	Pimozide
	Pralatrexate
	Rheumatrex Dose Pack
	Roxicodone
	Sansert
	Saphris
	Simvastatin
	Sublimaze
	Subsys
	Sucralfate
	Sufenta
	Sufentanil
	Tegretol
	Tegretol XR
	Teril
	Theo-24
	Theochron
	Theolair
	Theophylline
	Tizanidine
	Trexall
	Velban
	Versacloz
	Videx
	Videx EC
	Vinblastine
	Vincristine
	Vinorelbine
	Westadone
	Zanaflex
	Zinc
	Zocor
	Zyprexa
	Zyprexa Relprevv
	Zyprexa Zydis

Pregnancy Category:C

Breastfeeding: Probably Safe. Recent studies indicate little risk. The calcium in milk might prevent absorption of the small amounts of fluoroquinolones in milk, but insufficient data exist to prove or disprove this assertion. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 08 December 2010). Manufacturer recommends discontinuation of nursing or discontinuation of therapy by analyzing risk and benefit ratio in nursing mothers.

• EENT: Ear pruritus, fungal ear superinfection
• CNS: Headache
• LOCAL: Application site pain
• MISC: Hypersensitivity

• Fluoroquinolone; interferes with the enzyme DNA gyrase, which is needed for the synthesis of bacterial DNA
• Metabolism: Unknown; CYP450: Unknown
• Excretion: Unknown
• Half-life: Unknown

US Trade Name(s)

• Cetraxal

US Availability

Cetraxal

• OTIC SOLN: 0.2%

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• Ciloxan

Australian Availability

Ciloxan

• OTIC SOLN: 0.3%

[Outline]

Antimicrobials

Otic Anti-infectives

Infectious Disease

Otic Anti-infectives

ENT

Otic Anti-infectives