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General Reference

Nejm 1999;341:342

Pathophys and Cause

Cause:Genetic translocations

Epidemiology

4-7/million/yr in children <15 yr

Signs and Symptoms

Sx:Painless soft tissue mass

Course

70-80% cure unless mets, then 20% 5-yr survival

Lab and Xray

Lab:

Path:embryonal (good prognosis) or alveolar cell types

Treatment

Rx:Surgical removal then chemoRx