section name header

Synonym

Tubes

Additional information on specimen collection:

Info

Alkaline phosphatase (ALP) is the sum of a number of isoenzymes found in all body tissues. High concentrations are present in the liver bile duct placenta intestines and bones.

Clinical

The test is done to:

12 isoenzymes of ALP have been identified. The four main isoenzymes of clinical significance include:

Additional information:

Nl Result

Consult your laboratory for their normal ranges as these may vary somewhat from the ones listed below.

Reference ranges will be listed as Total alkaline phosphatase (T) Bone fraction (B) and Liver fraction (L).

T
(U/L)
B
(U/L)
L
(U/L)
Adult normals30-13010-700-93
16-20 year olds (F)25-12514-850-50
16-20 year olds (M)45-35025-3000-40
14 year olds (F)50-25030-2005-50
14 year olds (M)110-47580-3905-50
9-12 year olds (F)100-45080-3505-60
9-12 year olds (M)110-47580-3405-80
6 year olds70-37550-3005-75
1-5 year olds60-37540-3005-100

High Result

An elevation of Serum ALP to less than three times the upper range of normal is "non-specific " meaning that it often is not useful in establishing any specific diagnosis.

Increased serum ALP is seen in the following conditions:

Liver conditions:

Bone conditions:

Non-liver non-bone conditions:

Normal or increased serum ALP levels maybe seen in:

Drugs that may increase serum ALP levels include:

Low Result

Low serum ALP levels are seen in:

Normal or decreased serum ALP levels maybe seen in:

Marked decline of the high ALP in pregnancy may indicate:

ALP level may be transiently low after blood transfusion. This may be due to zinc chelation.

Drugs that may decrease the serum ALP levels include:

References

Synonym

Tubes

Info

Clinical

Nl Result

High Result

Low Result

References