Adult Dosing
Severe hypoglycemia
- 1 mg SC, IM, IV
- May repeat within 15 minutes
Diagnostic aid for radiographic examination of stomach, duodenum, and small intestine
- 1-2 mg IM or 0.25-2 mg IV 10 min before the procedure
- For relaxation of the stomach, use 0.5 mg IV or 2 mg IM 10 min prior to procedure; for colon 2 mg IM 10 min prior to procedure
Beta blocker overdose (Non FDA approved)
- Start 0.05 mg/kg IV over 1-2 mins x 1
- May be followed by a continuous IV infusion at a rate of 2-5 mg/hr (MAX: 10 mg/hr)
Calcium channel blocker overdose (Non FDA approved)
- Start 0.05 mg/kg IV over 1-2 mins x 1
- May be followed by a continuous IV infusion at a rate of 2-5 mg/hr (MAX: 10 mg/hr)
Pediatric Dosing
Severe hypoglycemia
- Child < 20 kgs: 0.5 mg or 0.02–0.03 mg/kg. May be repeated in 15 min if necessary
- Child > 20 kgs: 1 mg SC, IM, IV. May be repeated in 15 min if necessary
If weight is not known
- Child < 6-8 yrs: 0.5 mg
- Child > 6-8 yrs: 1 mg
[Outline]
- Administer cautiously to patients with a hx suggestive of insulinoma, pheochromocytoma, or both. In patients with insulinoma, IV administration may produce an initial increase in blood glucose. However, due to glucagon’s hyperglycemic effect the insulinoma may release insulin and cause subsequent hypoglycemia. Administer glucose orally or IV in such patients
- Seek emergency assistance and administer i.v.glucose if patient does does not respond within 15 min after SC or IM glucagon inj. Injection may be repeated while waiting for assistance. Give Oral Carbohydrate when the patient has responded to the treatment
- Glucagon is effective in treating hypoglycemia only if sufficient liver glycogen is present. It may not be beneficial in states of starvation, adrenal insufficiency, or chronic hypoglycemia
- Monitor blood sugars frequently in hypoglycemic patient until the patient is asymptomatic
- Monitor BP and pulse after administering glucagon. Be prepared to administer phentolamine to reduce BP in patient with pheochromocytoma or with coronary artery disease
Cautions : Use cautiously in
- History suggestive of insulinoma
- History suggestive of pheochromocytoma
- Elderly patients
- Prolonged fasting
- Starvation
- Adrenal insufficiency
- Chronic hypoglycemai
Pregnancy Category:B
Breastfeeding: Safety unknown. Manufacturer advises caution
US Trade Name(s)
US Availability
glucagon(generic)
- PWDR for INJ: 1 mg (1 unit)/vial
GlucaGen
Canadian Trade Name(s)
Canadian Availability
glucagon(generic)
GlucaGen, GlucaGen Hypokit
UK Trade Name(s)
UK Availability
GlucaGen Hypokit
Australian Trade Name(s)
Australian Availability
GlucaGen Hypokit
- PWDR for INJ: 1 mg (1 IU)/vial
[Outline]
Pricing data from www.DrugStore.com in U.S.A.
- GlucaGen HypoKit 1 MG SOLR [Box] (NOVO NORDISK)
1 mg = $152.53
3 mg = $442.38 - Glucagon Emergency 1 MG KIT [Box] (LILLY)
1 mg = $140.99
3 mg = $384.96
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.