Adult Dosing
Seizure disorder; adjunctive therapy
- 0.2 mg/kg PR x 1; may repeat dose in 4-12 hrs
- Max: 1 episode/5 days; 5 episodes/month
- Note: Since AcuDial system delivers in 2.5 mg increments, the prescribed dose is obtained by rounding upward to the next available dose
Pediatric Dosing
Seizure disorder; adjunctive therapy
- 2-5 yrs:
- 0.5 mg/kg PR x 1; may repeat dose in 4-12 hrs
- Max: 1 episode/5 days; 5 episodes/month
- Note: Since AcuDial system delivers in 2.5 mg increments, the prescribed dose is obtained by rounding upward to the next available dose
- 6-11 yrs:
- 0.3 mg/kg PR x 1; may repeat dose in 4-12 hrs
- Max: 1 episode/5 days; 5 episodes/month
- Note: Since AcuDial system delivers in 2.5 mg increments, the prescribed dose is obtained by rounding upward to the next available dose
- >11 yrs:
- 0.2 mg/kg PR x 1; may repeat dose in 4-12 hrs
- Max: 1 episode/5 days; 5 episodes/month
- Note: Since AcuDial system delivers in 2.5 mg increments, the prescribed dose is obtained by rounding upward to the next available dose
[Outline]
- Diazepam produces CNS depression. Caution patients against engaging in hazardous activities requiring mental alertness, such as operating machinery, driving a motor vehicle, or riding a bicycle
- Potential for a synergistic CNS-depressant effect when used simultaneously with alcohol or other CNS depressants must be considered
- Prolonged CNS depression has been observed in neonates treated with diazepam. Use not recommended in children under six months of age
- It may be used in patients with open angle glaucoma who are receiving appropriate therapy but is contraindicated in acute narrow angle glaucoma
- Use cautiously in the elderly, may accumulate and lead to psychomotor impairment
- Monitor CBC, LFTs if prolonged therapy
Cautions: Use cautiously in
Pregnancy Category:D
Breastfeeding: Safety unknown. Due to long half-life of diazepam and nordiazepam, timing breastfeeding with respect to the dose would be of little benefit in reducing infant exposure. Other agents should be preferred, especially while nursing a newborn or preterm infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 02 November 2009).
Pricing data from www.DrugStore.com in U.S.A.
- Diastat AcuDial 10 MG GEL [Box] (VALEANT)
1 mg = $423.99
3 mg = $1228.97 - Diastat AcuDial 20 MG GEL [Box] (VALEANT)
1 mg = $365.99
3 mg = $1059.97
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
