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General Reference

Nejm 1984;310:298

Pathophys and Cause

Cause:

Ascariasis: Ascaris lumbricoides, pig roundworm

Trichuriasis: Trichuris trichiura

Epidemiology

Highest incidence of both is in tropics, where eggs survive more easily, and in children, who do more fecal–oral transmission

Ascariasis: fecal–oral spread, 2-wk incubation of eggs necessary outside body before infective

Trichuriasis: fecal–oral spread

Signs and Symptoms

Sx:

Ascariasis: only if abnormal site or so many that they block gi tract. After ingestion, migrate to lungs, then coughed up, reingested

Trichuriasis: imbed in superficial intestinal mucosa, mainly colon; no tissue reaction, hence occasionally diarrhea

Complications

Ascariasis: small bowel obstruction; perforated bowel; asphyxia due to aspiration; biliary obstruction; hepatic abscess

Trichuriasis: anemia, malnutrition; rectal prolapse; allergic pneumonitis (in 10%) (rx w steroids–Weinstein, 1987)

Lab and Xray

Lab:

Bact:Ascariasis: stool shows eggs, and adults

Trichuriasis: stool shows barrel-shaped eggs w mucus plug at both ends; adults, whip is head end, handle is tail end

Treatment

Rx:

(Nejm 1996;334:1178)

Avoid reinfection; worms live <2 yr