Cause:Benign transformation of germ cell after first meiotic division
Pathophys:Contain ectodermal, mesodermal, and endodermal elements
Most common in young reproductive females; 15% of all ovarian tumors, 20-40% of all ovarian tumors of pregnancy
Sx:Pain with hemorrhage into tumor, with torsion, or rupture; usually asx
Si:Pelvic mass; 10-20% are bilateral
R/o ovarian cancer; dysgerminoma similar to male seminoma (Testicular Carcinomas (Seminoma, Embryonal [Germ] Cell Carcinoma, Teratoma, Choriocarcinoma)); thyrotoxicosis from proliferation of thyroid elements (struma ovarii); carcinoid sx also possible but rarer
Lab:Path:Bone, teeth, etc (all 3 layers of embryonal tissues)
Xray:
KUB may show bone, teeth, etc
Ultrasound usually diagnostic
Rx: Surgery; any teratoma with mature elements can be assumed to be benign and rx'd with simple ovarian cystectomy so both ovaries are preserved