Adult Dosing
Corticosteroid-responsive dermatoses w/ secondary infection
- Apply a small quantity of cream bid-qid, PRN. Cream should, if conditions permit, be gently rubbed into the affected areas
Pediatric Dosing
- Safety and effectiveness in pediatric patients have not been established
[Outline]
See Supplemental Patient Information
- Nephrotoxicity and ototoxicity may be associated with neomycin use. Hence, do not use this combination over a wide area or for extended periods of time
- Prolonged therapy may result in overgrowth of nonsusceptible organisms, including fungi
- If the infection is not improved after 1 week, cultures and susceptibility tests should be repeated to verify the organism and to determine whether therapy should be changed
- Use of steroids on infected areas should be cautiously supervised as anti-inflammatory steroids may encourage spread of infection. Discontinue steroid therapy and use appropriate anti-bacterial drugs, if this occurs
- Generalized dermatological conditions may require systemic corticosteroid therapy
- Therapy may cause signs and symptoms of exogenous hyperadrenocorticism, including adrenal suppression
- Systemic absorption increases if topical steroids are applied over large body surface areas or if occlusive dressings are used; caution should be exercised when long-term use is anticipated
- Neomycin may cause cutaneous sensitization; promptly discontinue therapy if sensitization or irritation occurs
- Allergic cross-reactions may occur, which could prevent future use of any or all of the aminoglycoside antibiotics
- Systemic effects of excessive levels of hydrocortisone may include a decrease in number of circulating eosinophils and a reduction in urinary excretion of 17-hydroxycorticosteroids
Caution: Use cautiously in
Supplemental Patient Information
- Instruct patients not to use in the eyes
- Advise patients to discontinue use and inform a physician if redness, irritation, swelling or pain persists or increases
Pregnancy Category:C
Breastfeeding: Safety unknown for combination drug. As per manufacturer's data, caution should be exercised while using in nursing women. Topical hydrocortisone is absorbed systemically and may have minimal excretion in breastmilk. Topical neomycin is excreted in very low levels in breastmilk and presents negligible risk to the infant; however, topical application to the nipple may increase the risk of diarrhea in the infant. Polymyxin B is minimally absorbed after topical application; therefore, it poses a low risk to the nursing infant.
Pricing data from www.DrugStore.com in U.S.A.
- Cortisporin 0.5-0.5-10000 CREA [Tube] (MONARCH PHARMACEUTICALS)
7.5 = $54.99
22.5 = $164.97
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
