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Pathophys and Cause

Cause:Idiopathic; alcoholic spider angiomata; aluminum workers in vest pattern (Nejm 1980;303:1278); OSLER-WEBER-RENDU SYNDROMEw autosomal dominant telangiectasias of brain, skin, gi tract, liver (Nejm 2000;343:931), etc

Treatment

Rx:SBE prophylaxis if possible pulmonary AVMs; support group (800-448-6389); various laser rx's possible (Med Let 1991;33:104);epsilon-aminocaproic acid rx may decrease bleeding in Osler-Weber-Rendu (Nejm 1994;330:1789)