Adult Dosing

Antacid

• 500-1500 mg PO q4-8 daily

Pediatric Dosing

• Safety and effectiveness in pediatric patients have not been established

[Outline]

• Adult Dosing
• Pediatric Dosing

• Treatment of heartburn or acid indigestion and sour stomach

• Hypersensitivity to any of the ingredients of the product
• GI obstruction
• Severe abdominal pain of unknown cause
• High doses in pregnancy

• N/A

Renal Dose Adjustment

• Renal impairment: Caution advised; dose adjustments not defined

Hepatic Dose Adjustment

• Hepatic impairment: No dose adjustments

• Do not administer other medication at the same time with aluminum hydroxide, as it hampers the absorption of certain drugs

Cautions: Use cautiously in

• Renal impairment
• Severe constipation
• Dehydration
• Chronic alcohol abuse

Pregnancy Category:NR

Breastfeeding: No published information available on use of aluminum, antacid therapy in nursing mother. Additional intake of this mineral by mother is unlikely to surpass that found in other infant foods; also oral absorption of aluminum is poor. Hence antacid use during breastfeeding is acceptable and no special precautions are required. This information is based upon Lactmed database (available athttp://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 6 April 2011).

• GI: Abdominal pain, constipation
• METABOLIC: Hypophosphatemia

• Antacid; neutralizes hydrochloric acid in gastric secretions, also inhibits the action of pepsin by increasing the pH and via adsorption
• 17-30% systemic absorption
• Not metabolized
• Excreted in feces and urine
• Half-life: Unknown

US Trade Name(s)

• only generic available

US Availability

aluminum hydroxide (generic)

• OTC SUSP: 320 mg/5 mL
• OTC SUSP: 600 mg/5 mL

Canadian Trade Name(s)

• N/A

Canadian Availability

• N/A

UK Trade Name(s)

• N/A

UK Availability

• N/A

Australian Trade Name(s)

• Alu-Tab

Australian Availability

Alu-Tab

• TABS: 600 mg

[Outline]

Gastrointestinal

Antacids