Cause:Genetic; chemical leukoderma, Addisons, pernicious anemia, tinea versicolor, tuberous sclerosis (present at birth); autoimmune autoantibodies to melanocytes in SLE, Graves disease, Hashimotos, diabetes, alopecia areata, rheumatoid arthritis; albinism (genetic, associated with actinic keratoses, cancers, nystagmus)
Rx:
Often used in combinations.