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General Reference

Jama 2005;293:730

Pathophys and Cause

Cause:Genetic; chemical leukoderma, Addison’s, pernicious anemia, tinea versicolor, tuberous sclerosis (present at birth); autoimmune autoantibodies to melanocytes in SLE, Graves’ disease, Hashimoto’s, diabetes, alopecia areata, rheumatoid arthritis; albinism (genetic, associated with actinic keratoses, cancers, nystagmus)

Treatment

Rx:

Often used in combinations.