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Use and Dosing

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Hypertension

Note:

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[Outline]

Indications

Contraindications

Black Box Warnings

Dosing Adjustment

Renal Dose Adjustment (Based on CrCl)

Hepatic Dose Adjustment

Warnings/Precautions

Cautions: Use cautiously in

Pregnancy/Breast Feeding

Pregnancy Category:D

Breastfeeding: As low level of benazepril is excreted in breastmilk, amount ingested by the infant is small and would not be expected to cause any adverse effects in breastfed infants. During lactation hydrochlorothiazide at a dose of 50 mg daily or less is acceptable. Intense diuresis with large doses may decrease breastmilk production. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 21 February 2011). As per manufacturer's data minimal amount of benazepril and benazeprilat are excreted into the breast milk and thiazides are definitely excreted into breast milk. Because of the potential for serious adverse reactions from hydrochlorothiazide and the unknown effects of benazepril in nursing infants, a decision should be made whether to discontinue nursing or to discontinue benazepril/hydrochlorothiazide taking into account the importance of the drug to the mother.

Adverse Reactions

Clinical Pharmacology

Benazepril

Hydrochlorothiazide

Brands and Availability

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US Trade Name(s)

US Availability

benazepril/hydrochlorothiazide (generic)

Lotensin HCT (benazepril/hydrochlorothiazide)

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Canadian Trade Name(s)

Canadian Availability

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UK Trade Name(s)

UK Availability

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Australian Trade Name(s)

Australian Availability


[Outline]

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Classification

Cardiovascular

Antihypertensive Combinations

Pricing

Pricing data from www.DrugStore.com in U.S.A.

Warning.gifWarning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.

Pill