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Interacting Drugs

OBJECT DRUGS

Antiarrhythmics (CYP3A4 Substrates):

PRECIPITANT DRUGS

Antimicrobials:


Comment:

Although data are limited, any CYP3A4 inhibitor could increase the plasma concentrations of amiodarone, disopyramide, or quinidine. Toxicity including cardiac arrhythmias could result. Assume that all CYP3A4 inhibitors interact until proven otherwise.


Class 3: Assess Risk & Take Action if Necessary