Adult Dosing
Corneal ulcers
Ophthalmic solution
- Day 1: Instill 2 gtts in affected eye(s) q15 min x 6 hrs, then q30 min x 18 hrs
- Day 2: Instill 2 gtts in affected eye(s) q1 hr
- Days 3 through 14: Instill 2 gtts in affected eye(s) q4 hrs
- Note: May need to extend course if corneal re-epithelialization has not occurred
Bacterial conjunctivitis
Ophthalmic solution
- Days 1 & 2: Instill 1-2 gtts in affected eye(s) q2 hrs while awake
- Days 3 through 7: Instill 1-2 gtts in affected eye(s) q4 hrs for 5 days
Ophthalmic ointment
- Days 1 & 2: Apply 0.5 inch ribbon in conjunctival sac affected eye(s) tid
- Days 3 through 7: Apply 0.5 inch in affected eye(s) bid
Pediatric Dosing
Corneal ulcers
Child > 1 yr; ophthalmic solution
- Day 1: Instill 2 gtts in affected eye(s) q15 min x 6 hrs, then q30 min x 18 hrs
- Day 2: Instill 2 gtts in affected eye(s) q1 hr
- Days 3 through 14: Instill 2 gtts in affected eye(s) q4 hrs
- Note: May need to extend course if corneal re-epithelialization has not occurred
Bacterial conjunctivitis
Child > 1 yr; ophthalmic solution
- Days 1 & 2: Instill 1-2 gtts in affected eye(s) q2 hrs while awake
- Days 3 through 7: Instill 1-2 gtts in affected eye(s) q4 hrs for 5 days
Child > 2 yrs; ophthalmic ointment
- Days 1 & 2: Apply 0.5 inch ribbon in conjunctival sac affected eye(s) tid
- Days 3 through 7: Apply 0.5 inch in affected eye(s) bid
[Outline]
See Supplemental Patient Information
- Ophthalmic solution should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye
- Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have occurred with systemic quinolone therapy, even following a single dose
- Prolonged administration may cause bacterial superinfection
- Discontinue use immediately at the first sign of rash or allergic reaction
- May retard corneal healing and cause visual blurring
- Avoid contaminating the applicator tip with material from the eye, fingers or other source
- Advise patients to avoid using contact lenses during treatment period
Supplemental Patient Information
- Instruct patient on proper instillation technique and to remove contact lenses
Pregnancy Category:C
Breastfeeding: Maternal use of ophthalmic ciprofloxacin presents negligible risk for the nursing infant. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT). This drug is compatible and considered safe with breastfeeding based upon data from AAP Policy Guidelines (available at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;108/3/776 last accessed 20 August 2010)
Pricing data from www.DrugStore.com in U.S.A.
- Ciloxan 0.3 % OINT [Tube] (ALCON VISION)
3.5 % = $109.03
10.5 % = $292.19 - Ciprofloxacin HCl 0.3 % SOLN [Bottle] (SANDOZ)
10 % = $59.99
30 % = $159.96 - Ciprofloxacin HCl 0.3 % SOLN [Bottle] (SANDOZ)
5 % = $29.99
15 % = $79.96 - Ciloxan 0.3 % SOLN [Bottle] (ALCON VISION)
5 % = $83.9
15 % = $229.89
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.
