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General Reference ⬇

Am J Pub Hlth 1991;81:471

Pathophys and Cause ⬆ ⬇

Cause:Ingestion of shellfish contaminated with dinoflagellate (red tide) neurotoxin; when occurs with fish is called ciguatera poisoning (see scombroid)

Epidemiology ⬆ ⬇

Occurs in epidemics

Signs and Symptoms ⬆ ⬇

Sx:Cooking does not prevent; onset in 0.5-10 h. Paresthesias (81%); reversal of hot/cold sensations (17%); vertigo (60%); myalgias; abdominal pain (48%); nausea (44%); rectal burning; headache (15%)

Si:Ataxia (27%); bradycardia; dilated pupils

Course ⬆ ⬇

8-48 h

Treatment ⬆

Rx:Charcoal, respiratory support; mannitol 1-2 gm/kg; possibly calcium channel blockers, lidocaine