- Prior to initiating therapy, carefully evaluate risk and benefit ratio as smoking causes lung disease, cancer and heart disease, and may adversely affect pregnant women or the fetus
- Therapy can cause fetal harm when administered to a pregnant woman. Therefore the patient should be apprised of the potential hazard to the fetus
- Keep out of the reach of children and pets
- Discontinue therapy if clinically significant increase in cardiovascular or other adverse effects occur
- May cause bronchospasm, therefore should be used with caution in patients with bronchospastic disease
- Prior to administering therapy, carefully evaluate patients with coronary heart disease, serious cardiac arrhythmias, or vasospastic diseases as therapy is associated with tachycardia and palpitations
- Since nicotine causes the release of catecholamines by the adrenal medulla, therapy should be used with caution in patients with hyperthyroidism, pheochromocytoma or insulin-dependent diabetes
- Therapy should be used with caution in patients with active peptic ulcers because nicotine delays healing in peptic ulcer disease
- Therapy constitutes a risk factor for development of malignant hypertension in patients with accelerated hypertension, therefore therapy should be used with caution in these patients
Cautions: Use cautiously in
- Severe renal impairment
- Hepatic impairment
- Continued cigarette use
- Asthma or reactive airway disease
- Pulmonary disease
- Cardiovascular disease
- Peripheral vascular disease
- Hyperthyroidism
- Pheochromocytoma
- Insulin-dependent diabetes mellitus
- Active PUD
- Hypertension
Pregnancy Category:D
Breastfeeding: Some authors suggest that nicotine may increase the risk of sudden infant death syndrome and might interfere with normal infant lung development; an alternate agent may be preferred. This information is based upon LactMed database (available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT last accessed 21 February 2011).
US Trade Name(s)
US Availability
Nicotrol
Canadian Trade Name(s)
Canadian Availability
UK Trade Name(s)
- Nicorette Inhalator / Boots NicAssist
UK Availability
Nicorette Inhalator /Boots NicAssist
Australian Trade Name(s)
Australian Availability
Nicorette
[Outline]
Pricing data from www.DrugStore.com in U.S.A.
- Nicotrol NS 10 MG/ML SOLN [Bottle] (PFIZER U.S.)
40 ml = $207.1
120 ml = $595.12 - Nicotrol 10 MG INHA [Inhaler] (PFIZER U.S.)
168 mg = $212.94
504 mg = $604.54
Warning: This pricing information is subject to change at the sole discretion of DS Pharmacy. For the most current and up-to-date pricing information, please visit drugstore.com.