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Box

Noncardiac Adverse Effects of Amiodarone

In addition to adverse cardiovascular effects of amiodarone, other adverse effects include:

  • CNS—malaise, fatigue, dizziness, peripheral neuropathy, ataxia, paresthesia, tremors, headache, vision disturbances
  • Respiratory—pulmonary toxicity (progressive dyspnea, cough, fever, pleuritic chest pain)
  • GI—nausea, vomiting, constipation, anorexia, elevated liver function tests
  • Other—photosensitivity, abnormal taste and smell, hypothyroidism or hyperthyroidism, bleeding disorders, muscle weakness.