The healthcare provider needs basic knowledge about the procedure and test and should have the required skills to perform testing or to assist in the process. Safe practices, proper collection of specimens, minimizing delays, providing support to the patient, preparing or administering analgesia and sedatives, monitoring various bioparameters as necessary, and being alert to potential side effects or complications are integral activities of the intratest phase. Invasive procedures place patients at greater risk for complications and adverse events and require ongoing vigilance and observation. Monitoring fluid intake and loss, body temperature, and respiratory and cardiovascular systems and treating problems in these domains require critical thinking, quick responses, and appropriate treatment.