The aspergilli, especially Aspergillus fumigatus, Aspergillus flavus, and Aspergillus niger, are associated with pulmonary infections and invasive fatal disease sequelae in immunosuppressed patients. Manifestations of Aspergillus infections include allergic bronchopulmonary disease; lung mycetoma; endophthalmitis; and disseminated brain, kidney, heart, and bone disease.
This test detects antibodies present in aspergillosis, primarily allergic bronchopulmonary disease, or fungus ball.
Collect a 7-mL blood serum sample in a red-topped tube. CSF can also be tested. Observe standard precautions.
Label the specimen with the patient’s name, date, and tests ordered and place in a biohazard bag for transport to the laboratory.
Positive test results are associated with pulmonary infections in compromised patients and Aspergillus infections of prosthetic heart valves.
If blood serum exhibits one to four bands using ID, aspergillosis is strongly suspected. Weak bands suggest an early disease process or hypersensitivity pneumonitis.
Best use of the CF test is with paired sera taken 3 weeks apart to detect a rise in titer against a single antigen.
Pretest Patient Care
Explain test purpose and procedure.
Follow guidelines in Chapter 1 for safe, effective, informed pretest care.
Specimens for culture of the organism may also be required.
Posttest Patient Care
Review test results; report and record findings. Modify the nursing care plan as needed. Counsel the patient regarding abnormal findings; explain the need for possible follow-up testing and treatment. See Interpreting Results of Immunologic Tests.
Follow guidelines in Chapter 1 for safe, effective, informed posttest care.