Proper body positioning and alignment involves placing the patient in the best possible position for the procedure and aligning the body correctly for optimal respiratory and circulatory function. Positions include prone, lithotomy, sitting, supine, jackknife, and Trendelenburg. Use positioning devices, arrange padding, and reposition as needed to prevent skin pressure and skin breakdown. The potential adverse effects of various positions, especially during lengthy procedures, include skin breakdown, venous compression, sciatic nerve injury, muscle injury, and low back strain. Necessary positioning skills include ensuring that the patient’s airway, IV lines, skin integrity, and monitoring devices are not compromised and identifying those persons at potential risk for injury (e.g., older, thin, frail, sedated, or unconscious patients) before positioning. If wounds, skin breakdown, abrasions, or bruises are present before the procedure, accurately document their presence and location.