Several RBC enzyme and fragility tests can be done to screen, detect, and confirm the cause of chronic hemolytic anemia. Many persons with hemolytic anemia have no clinical signs or symptoms. Abnormal test outcomes are associated with inherited deficiencies, abnormal Hb, and exposure to chemicals and drugs. Definitive test results indicate some type of injury to the RBC, oxidative activity that interferes with normal Hb function, or increased RBC fragility.
Subtopic(s):