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Introduction

A prostate scan is performed using indium 111 (111In) capromab pendetide (brand name ProstaScint®) and is also known as a ProstaScint scan. This test is done to determine whether curative therapy and radiotherapy are treatment options in patients with biopsy-proven prostate cancer who are at high risk for metastasis or have a rising prostate-specific antigen following a prostatectomy.

Procedure

  1. The patient is injected with 5.5–6.5 mCi of 111In capromab pendetide intravenously over a 5-minute period.

  2. The patient then drinks 8–12 oz of water and undergoes the first imaging session.

  3. On day 3 (48 hours before second imaging session) and day 4 (24 hours before second imaging session), the patient is instructed to take an oral laxative. A cleansing enema should be performed just before arrival for the second imaging session, which is 5 days after injection.

  4. Depending on the results of the imaging sessions, a third imaging session on day 6 or 7 may be necessary.

Clinical Alert

ProstaScint is contraindicated in patients who are hypersensitive to murine-origin products

Clinical Implications

Increased activity or uptake in the lymph nodes indicates the likelihood of metastatic disease.

Interventions

Pretest Patient Care

  1. Explain the purpose, procedure, benefits, and risks of the test.

  2. Refer to standard nuclear imaging pretest precautions.

  3. Follow guidelines in Chapter 1 for safe, effective, informed pretest care.

Posttest Patient Care

  1. Refer to standard NMI posttest precautions.

  2. Review test results; report and record findings. Modify the nursing care plan as needed.

  3. Follow guidelines in Chapter 1 for safe, effective, informed posttest care.

Reference Values

Normal

No areas of uptake or ProstaScint activity.