Viral hepatitis A; can be IgM or IgG (if IgM, acute hepatitis A; if IgG, previous infection with hepatitis A)
See Fig. 26 for serologic tests in HAV infection.
Figure 26 Serologic tests in hepatitis A viral infection.
HAV, Hepatitis A virus; HAV-Ab, hepatitis A virus antibodies test; HAV-Ag, hepatitis A virus antigen test; Ig, immunoglobulin.
See Table E60 for serologic and virologic tests for hepatitis viruses.
TABLE E60 Serologic and Virologic Tests for Hepatitis Viruses
| IgM Anti-HAV | IgG Anti-HAV | HBsAg | Anti-HBs | IgM Anti-HBVc | HBeAg | Anti-HBe | HBV DNA | Anti-HCV Screen | HCV RNA | Anti-HDV | Anti-HEV | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HAV: | ||||||||||||
| Acute | + | + | ||||||||||
| Remote | + | + | ||||||||||
| HBV: | ||||||||||||
| Early | + | - | + | + | - | + | ||||||
| Window | - | - | + | - | - | + | ||||||
| Resolving | -/+ | + | - | -/+ | + | -/+ | ||||||
| Chronic | + | -/+ | - | + | +/- | + | ||||||
| TX monitoring | + | |||||||||||
| Remote | - | + | - | -/+ | +/- | -/+ | ||||||
| HCV: | ||||||||||||
| Screen | + | + | ||||||||||
| Acute | +/- | + | ||||||||||
| Chronic | + | + | ||||||||||
| TX monitoring | + | |||||||||||
| Remote | + | -/+ | ||||||||||
| HDV: | ||||||||||||
| Superinfection | + | - | +/- | + | -/+ | +/- | + | |||||
| HEV | + |
DNA, Deoxyribonucleic acid; HAV, hepatitis A virus; HBeAg, hepatitis E antigen; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; HCV, hepatitis C virus; HDV, hepatitis D virus; HEV, hepatitis E virus; Ig, immunoglobulin; RNA, ribonucleic acid; TX, Texas; +, positive; -, negative.
Data from CDC: Surveillance for acute hepatitis, United States, 2007, MMWR 58(SS-3), 2009. From McPherson RA, Pincus MR: Henry’s clinical diagnosis and management by laboratory methods, ed 23, Philadelphia, 2017, Elsevier.