Envisioned Uses of Brain Biomarkers for Severe Traumatic Brain Injury (TBI) Patient Management - Flowchart

Envisioned Uses of Brain Biomarkers for Severe Traumatic Brain Injury (TBI) Patient Management - Flowchart

Envisioned Uses of Brain Biomarkers for Severe Traumatic Brain Injury (TBI) Patient Management - Flowchart Traumatic Brain Injury Traumatic Brain Injury

«Flowchart»

TBI Patient

TBI Patient

TBI Patient

GCS @ Emergency Department/Paramedic

GCS @ Emergency Department/Paramedic

GCS @ Emergency Department/Paramedic

Severe TBI (GCS 3-8)

Severe TBI (GCS 3-8)

Severe TBI (GCS 3-8)

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

End

End

End

Repeated CSF Samples

Repeated CSF Samples

Repeated CSF Samples

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

Initial CSF Sample

Initial CSF Sample

Initial CSF Sample

Brain Physiologic Monitoring (ICP, O2)

Brain Physiologic Monitoring (ICP, O2)

Brain Physiologic Monitoring (ICP, O2)

Neuro-Intensive Care Unit

Neuro-Intensive Care Unit

Neuro-Intensive Care Unit

Decompressive Ventriculostomy

Decompressive Ventriculostomy

Decompressive Ventriculostomy

Cranial CT

Cranial CT

Cranial CT

Systemic Physiologic Monitoring (MAP, HR, etc.)

Systemic Physiologic Monitoring (MAP, HR, etc.)

Systemic Physiologic Monitoring (MAP, HR, etc.)

Initial Blood Sample

Initial Blood Sample

Initial Blood Sample

Repeated Blood Samples

Repeated Blood Samples

Repeated Blood Samples

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

TBI Biomarker Analysis & Monitoring

CSF, Cerebrospinal fluid; CT, computed tomography; GCS, Glasgow Coma Scale; HR, heart rate; ICP, intracranial pressure; MAP, mean arterial blood pressure.

CSF, Cerebrospinal fluid; CT, computed tomography; GCS, Glasgow Coma Scale; HR, heart rate; ICP, intracranial pressure; MAP, mean arterial blood pressure.

CSF, Cerebrospinal fluid; CT, computed tomography; GCS, Glasgow Coma Scale; HR, heart rate; ICP, intracranial pressure; MAP, mean arterial blood pressure.

CSF CT GCS HR ICP MAP