Treatment Options Based on Subtype of Systemic Mastocytosis - Flowchart
Treatment Options Based on Subtype of Systemic Mastocytosis - Flowchart Mastocytosis Mastocytosis
«Flowchart»

Diagnosis of SM

Diagnosis of SM

Diagnosis of SM

Midostaurin; 2-CdA or IFN-; clinical trial; multi-agent chemotherapy for MCL; allogeneic HSCT

Midostaurin; 2-CdA or IFN-; clinical trial; multi-agent chemotherapy for MCL; allogeneic HSCT

Midostaurin; 2-CdA or IFN-; clinical trial; multi-agent chemotherapy for MCL; allogeneic HSCT

End

End

End

Drugs for mediator symptoms

Drugs for mediator symptoms

Drugs for mediator symptoms

Observe

Observe

Observe

Organ damage?

Which disease requires treatment?

Organ damage?

Which disease requires treatment?

Organ damage?

Which disease requires treatment?

AHN-directed treatment

AHN-directed treatment

AHN-directed treatment

Midostaurin; 2-CdA or IFN-; or clinical trial

Midostaurin; 2-CdA or IFN-; or clinical trial

Midostaurin; 2-CdA or IFN-; or clinical trial

Refractory?

Refractory?

Refractory?

2-CdA or IFN- or clinical trial

2-CdA or IFN- or clinical trial

2-CdA or IFN- or clinical trial

ASM/MCL

ASM/MCL

ASM/MCL

SM-AHN

SM-AHN

SM-AHN

ISM or SSM Symptomatic

ISM or SSM Symptomatic

ISM or SSM Symptomatic

ISM Asymptomatic

ISM Asymptomatic

ISM Asymptomatic