Sinusoidal and portal hypertension

Splanchnic arterial vasodilation

Decreased effective arterial blood volume

High-pressure baroreceptor mediated activation of renin-angiotensin-aldosterone and sympathetic nervous systems and arginine vasopressin

Sodium and water retention

Normalization of the activity of sodium- and water-retaining systems

Normal sodium and water excretion

No ascites

Ascites formation

Hepatorenal syndrome

End

Increase in plasma volume

Adequate to normalize circulatory homeostasis

Inadequate to normalize circulatory homeostasis

Persistent activation of sodium- and water-retaining systems

Continuous sodium and water retention

Renal vasoconstriction