Laboratory Diagnosis of Human Immunodeficiency Virus (HIV) Infection - Flowchart
Laboratory Diagnosis of Human Immunodeficiency Virus (HIV) Infection - Flowchart Human Immunodeficiency Virus Human Immunodeficiency Virus
«Flowchart»

HIV-1/2 antigen/antibody combination immunoassay (4th generation immunoassay)

HIV-1/2 antigen/antibody combination immunoassay (4th generation immunoassay)

HIV-1/2 antigen/antibody combination immunoassay (4th generation immunoassay)

th

Negative for HIV-1 and HIV-2 antibodies and p24 antigen

Negative for HIV-1 and HIV-2 antibodies and p24 antigen

Negative for HIV-1 and HIV-2 antibodies and p24 antigen

(+)

(+)

(+)

(–)

(–)

(–)

End

End

End

HIV2 antibodies detected

HIV2 antibodies detected

HIV2 antibodies detected

HIV1 antibodies detected

HIV1 antibodies detected

HIV1 antibodies detected

HIV antibodies detected

HIV antibodies detected

HIV antibodies detected

HIV-1
NAAT

HIV-1
NAAT

HIV-1
NAAT


HIV1 and HIV2 specific immunoassays

HIV1 and HIV2 specific immunoassays

HIV1 and HIV2 specific immunoassays

HIV1 (+)
HIV2 (–)

HIV1 (+)
HIV2 (–)


HIV1 (+)

HIV1 (–)
HIV2 (+)

HIV1 (–)
HIV2 (+)


HIV1 (–)

HIV1 (+)
HIV2 (+)

HIV1 (+)
HIV2 (+)


HIV1 (+)

HIV1 (–) or indeterminate
HIV2 (–)

HIV1 (–) or indeterminate
HIV2 (–)


HIV1 (–) or indeterminate

(+) indicates reactive result
(–) indicates nonreactive result
NAAT: Nucleic acid amplification testing

(+) indicates reactive result
(–) indicates nonreactive result
NAAT: Nucleic acid amplification testing

(+) indicates reactive result
(–) indicates nonreactive result
NAAT: Nucleic acid amplification testing



HIV-1
NAAT (+)
Acute HIV infection

HIV-1
NAAT (+)
Acute HIV infection



HIV-1

HIV-1
NAAT (–)
Negative for HIV-1

HIV-1
NAAT (–)
Negative for HIV-1



HIV-1