Suggested Algorithm for the Management of Cutaneous Manifestations in Systemic Lupus Erythematosus - Flowchart
Suggested Algorithm for the Management of Cutaneous Manifestations in Systemic Lupus Erythematosus - Flowchart Systemic Lupus Erythematosus Systemic Lupus Erythematosus
«Flowchart»

Dermatologic SLE

Dermatologic SLE

Dermatologic SLE

Dermatologic SLE

1st line treatment

Topical: GC or CNI
+
Systemic GC

1st line treatment

Topical: GC or CNI
+
Systemic GC

1st line treatment

1st line treatment

Topical: GC or CNI
+
Systemic GC

Topical: GC or CNI
+
Systemic GC

1st line treatment

Topical: GC or CNI

1st line treatment

Topical: GC or CNI

1st line treatment

1st line treatment

Topical: GC or CNI

Topical: GC or CNI or

    UVA + UVB protection
    Smoking cessation
    HCQ
    plus

    UVA + UVB protection
    Smoking cessation
    HCQ
    plus

    UVA + UVB protection
    Smoking cessation
    HCQ
    plus

UVA + UVB protection UVA + UVB protection
Smoking cessation Smoking cessation
HCQ
plus HCQ
plus

Mild - limited

Mild - limited

Mild - limited Mild - limited

Moderate - severe

Moderate - severe

Moderate - severe Moderate - severe

<Next Node>

<Next Node>

<Next Node>

<Next Node>

End

End

End

Response

Response

Response

Response

Yes

Yes

Yes Yes

No

No

No No

2nd line treatment

MTX

2nd line treatment

MTX

2nd line treatment

2nd line treatment

MTX

MTX

Response

Response

Response

Response

Yes

Yes

Yes Yes

No

No

No No

Response

Response

Response

Response

Yes

Yes

Yes Yes

No

No

No No

4th line treatment

Rituximab or Thalidomide

4th line treatment

Rituximab or Thalidomide

4th line treatment

4th line treatment

Rituximab or Thalidomide

Rituximab or Thalidomide

3rd line treatment

MMF or Dapsone or Retinoids or Belimumab

3rd line treatment

MMF or Dapsone or Retinoids or Belimumab

3rd line treatment

3rd line treatment

MMF or Dapsone or Retinoids or Belimumab

MMF or Dapsone or Retinoids or Belimumab

Yes

Yes

Yes Yes

No

No

No No