Dengue and Zika Virus Testing Recommendations for Nonpregnant Persons With a Clinically Compatible Illness and Risk for Infection With Both Viruses

Dengue and Zika Virus Testing Recommendations for Nonpregnant Persons With a Clinically Compatible Illness and Risk for Infection With Both Viruses - Flowchart Dengue Fever Dengue Fever

«Flowchart»

Start

Acute dengue virus infection

End

Perform dengue and Zika virus NAATs

Positive dengue virus NAAT

Positive Zika virus NAAT

Negative dengue and Zika virus NAATs

Acute Zika virus infection

Recent flavivirus infection

Recent dengue virus infection

Recent Zika virus infection

No evidence of dengue or Zika virus infection

Perform dengue and Zika virus IgM serology

Positive dengue or Zika virus IgM

Negative dengue and Zika virus IgM

Specimen collected ≤7 days postsymptom onset

≤ Specimen collected <=7 days

Specimen collected >7 days postsymptom onset

Specimen collected >7 days

Perform dengue and Zika virus PRNTs

Dengue virus PRNT ≥10 and Zika virus PRNT <10

≥ Dengue virus PRNT >=10 and Zika virus PRNT <10

Dengue virus PRNT <10 and Zika virus PRNT ≥10

≥ Dengue virus PRNT <10 and Zika virus PRNT >=10

Dengue virus PRNT ≥10 and Zika virus PRNT ≥10

≥ ≥ Dengue virus PRNT >=10 and Zika virus PRNT >=10

Dengue virus PRNT <10 and Zika virus PRNT <10