INADEQUATE INSULIN SECRETION

↑ Fatty acid oxidation

↑ Gluconeogenesis

↑ Glycogenolysis

↓ Peripheral glucose uptake and metabolism

HYPERGLYCEMIA

KETONE BODIES

ACIDOSIS

DEHYDRATION

End

Renal potassium loss

Poor tissue perfusion

Increased lactate

Renal phosphate loss

Hyperkalemia

Increased insensible fluid losses

Vomiting

Osmotic diuresis

DEHYDRATION

Renal sodium loss