Algorithms for Management of AIDS-Associated Kaposi Sarcoma (KS) - Flowchart
Algorithms for Management of AIDS-Associated Kaposi Sarcoma (KS) - Flowchart Kaposi Sarcoma Kaposi Sarcoma
«Flowchart»

Histologic confirmation of KS

Histologic confirmation of KS

Histologic confirmation of KS

Poor risk (T1)
Rapid progressive mucocutaneous disease

Poor risk (T1)
Rapid progressive mucocutaneous disease

Poor risk (T1)
Rapid progressive mucocutaneous disease


Intralesional chemotherapy (vinblastine, vincristine, bleomycin)
Radiotherapy
Topical retinoids
Cryotherapy
Photocoagulation

Intralesional chemotherapy (vinblastine, vincristine, bleomycin)
Radiotherapy
Topical retinoids
Cryotherapy
Photocoagulation

Intralesional chemotherapy (vinblastine, vincristine, bleomycin)
Radiotherapy
Topical retinoids
Cryotherapy
Photocoagulation





Continue cART

Continue cART

Continue cART

Start cART

Start cART

Start cART

No progression

No progression

No progression

Local progression

Local progression

Local progression

Rapid/systemic progression

Rapid/systemic progression

Rapid/systemic progression

End

End

End

cART plus: Pegylated liposomal doxorubicin, or Liposomal daunorubicin

cART plus: Pegylated liposomal doxorubicin, or Liposomal daunorubicin

cART plus: Pegylated liposomal doxorubicin, or Liposomal daunorubicin

Paclitaxel

Paclitaxel

Paclitaxel

Oral etoposide
Clinical trials

Oral etoposide
Clinical trials

Oral etoposide
Clinical trials


H and P (including oral cavity and entire skin)
Stool for occult blood
CXR
CD4 count
HIV viral load

H and P (including oral cavity and entire skin)
Stool for occult blood
CXR
CD4 count
HIV viral load

H and P (including oral cavity and entire skin)
Stool for occult blood
CXR
CD4 count
HIV viral load





Poor risk (T1)
Rapid progressive mucocutaneous disease

Poor risk (T1)
Rapid progressive mucocutaneous disease


Poor risk (T1)