Dengue and Zika Virus Testing Recommendations for Pregnant Persons With a Clinically Compatible Illness and Risk for Infection With Both Viruses

Dengue and Zika Virus Testing Recommendations for Pregnant Persons With a Clinically Compatible Illness and Risk for Infection With Both Viruses - Flowchart Dengue Fever Dengue Fever

«Flowchart»

Specimen collected ≤12 wk postsymptom onset

≤

Acute dengue virus infection

Acute Zika virus infection

End

Flavivirus infection

Zika virus infection

Dengue virus infection

No evidence of dengue or Zika virus infection

Perform dengue and Zika virus PRNTs

Dengue virus PRNT ≥10 and Zika virus PRNT <10

≥ Dengue virus PRNT >=10 and Zika virus PRNT <10

Dengue virus PRNT <10 and Zika virus PRNT ≥10

≥ Dengue virus PRNT <10 and Zika virus PRNT >=10

Dengue virus PRNT ≥10 and Zika virus PRNT ≥10

≥ ≥ Dengue virus PRNT >=10 and Zika virus PRNT >=10

Dengue virus PRNT <10 and Zika virus PRNT <10

Perform dengue and Zika virus NAATs and dengue and Zika virus IgM serology

Positive dengue virus NAAT

Positive Zika virus NAAT

Negative dengue and Zika virus NAATs and positive dengue and Zika virus IgM

Negative dengue and Zika virus NAATs and negative dengue and Zika virus IgM