Schematic Diagram of the Effect of Smoking on Airway Inflammation and Structural Components of Alveolar Walls—the Latter by Altering the Relationship Between Elastase and 1-antitrypsin (also called 1-protease inhibitor)

Schematic Diagram of the Effect of Smoking on Airway Inflammation and Structural Components of Alveolar Walls—the Latter by Altering the Relationship Between Elastase and 1-antitrypsin (also called 1-protease inhibitor) - Flowchart

«Flowchart»

Smoking

Increased mucus production

Impaired mucociliary clearance

Oxidative stress

Recruitment of inflammatory cells

CHRONIC BRONCHITIS

End

CHRONIC BRONCHITIS

CHRONIC BRONCHITIS CHRONIC BRONCHITIS

EMPHYSEMA

EMPHYSEMA EMPHYSEMA

1-antitrypsin

Tissue inhibitors of matrix metalloproteinases

Elastase

Matrix metalloproteinases

EMPHYSEMA