Severe trauma, hyperthermia, polymyositis/dermatomyositis, carbon monoxide poisoning, drugs (narcotic and amphetamine toxicity), hypothyroidism, muscle ischemia
Table 129 differentiates hematuria and hemoglobinuria from myoglobinuria.
TABLE 129 Differentiation of Hematuria, Hemoglobinuria, and Myoglobinuria
| Condition | Plasma Findings | Urine Findings |
|---|---|---|
| Hematuria | Color-normal | Color-normal, smoky, pink, red, brown |
| Erythrocytes-many | ||
| Renal-red blood cell casts | ||
| Protein-marked increase | ||
| Lower urinary tract-no casts | ||
| Protein-present or absent | ||
| Hemoglobinuria | Color-pink (early) | Color-pink, red, brown |
| Haptoglobin-low | Erythrocytes-occasional | |
| Pigment casts-occasional | ||
| Protein-present or absent | ||
| Hemosiderin-late | ||
| Myoglobinuria | Color-normal | Color-red, brown |
| Haptoglobin-normal | Erythrocytes-occasional | |
| Creatine kinase-marked increase | Dense brown casts-occasional | |
| Aldolase-increased | Protein-present or absent |
From McPherson RA, Pincus MR: Henry’s clinical diagnosis and management by laboratory methods, ed 23, St Louis, 2017, Elsevier.