The clinical presentation of acute kidney injury (AKI) depends on the presence of any preexisting conditions, the precipitating event(s) that caused the AKI and the severity of the AKI
The clinical presentation of acute kidney injury (AKI) depends on the presence of any preexisting conditions, the precipitating event(s) that caused the AKI and the severity of the AKI Acute Kidney injury Acute Kidney injury
«Flowchart»

PRE-EXISTING CONDITIONS

Reduced effective
circulating volume


Cardiac failure
Cirrhosis
(Nephrotic syndrome)

Hypertension

Atherosclerosis


Renal artery stenosis
Aortic aneurysm

Diabetes


Chronic renal disease


Single functioning kidney


Obstruction


Bladder neck
Ureteric


Malignancy


Prostate cancer
Bowel cancer
Cervical cancer
Lymphoma

PRE-EXISTING CONDITIONS

Reduced effective
circulating volume


Cardiac failure
Cirrhosis
(Nephrotic syndrome)

Hypertension

Atherosclerosis


Renal artery stenosis
Aortic aneurysm

Diabetes


Chronic renal disease


Single functioning kidney


Obstruction


Bladder neck
Ureteric


Malignancy


Prostate cancer
Bowel cancer
Cervical cancer
Lymphoma

PRE-EXISTING CONDITIONS

Reduced effective
circulating volume


Cardiac failure
Cirrhosis
(Nephrotic syndrome)

Hypertension

Atherosclerosis


Renal artery stenosis
Aortic aneurysm

Diabetes


Chronic renal disease


Single functioning kidney


Obstruction


Bladder neck
Ureteric


Malignancy


Prostate cancer
Bowel cancer
Cervical cancer
Lymphoma




Reduced effective
circulating volume


Cardiac failure
Cirrhosis
(Nephrotic syndrome)


Cardiac failure
Cirrhosis
(Nephrotic syndrome) Hypertension

Atherosclerosis


Renal artery stenosis
Aortic aneurysm


Renal artery stenosis
Aortic aneurysm

Diabetes

Diabetes


Chronic renal disease


Chronic renal disease


Single functioning kidney


Single functioning kidney


Obstruction


Obstruction


Bladder neck
Ureteric


Bladder neck
Ureteric
Malignancy


Prostate cancer
Bowel cancer
Cervical cancer
Lymphoma



Prostate cancer
Bowel cancer
Cervical cancer
Lymphoma



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Acute obstruction

Acute obstruction

Acute obstruction

Acute obstruction

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Risk

Risk

Risk

Risk

End

End

End

Recovery

Recovery

Recovery Recovery

Injury

Injury

Injury Injury

End

End

End

Recovery

Recovery

Recovery Recovery

Failure

Failure

Failure Failure

End

End

End

Recovery

Recovery

Recovery

Recovery

Irreversible loss of renal function

Irreversible loss of renal function

Irreversible loss of renal function Irreversible loss of renam function

Reversible loss of renal function

Reversible loss of renal function

Reversible loss of renal function Reversible lossof renal function

Acute hypovolaemia
Hypotension
Vasodilation

Acute hypovolaemia
Hypotension
Vasodilation



Acute hypovolaemia Hypotension Vasodilation

Sepsis and septic shock

Sepsis and septic shock

Sepsis and septic shock

Decreased cardiac output

Decreased cardiac output

Decreased cardic output

PRERENAL

PRERENAL

PRERENAL PRERENAL

RENAL

RENAL

RENAL RENAL

POSTRENAL

POSTRENAL

POSTRENAL POSTRENAL

Radiocontrast

Radiocontrast

Radiocontrast

Rhabdomyolysis

Rhabdomyolysis

Rhabdomyolysis

Drug

Drug

Drug

Drug

Drug

Drug