Start

Prognosis or added risk stratification

Diagnosis

Prevention

ACC/AHA Stage A/B HF

ACC/AHA Stage C/D HF

ACC/AHA Acute/Hospitalized HF

Acute dyspnea to ED / Hospitalized for ADHF

BNP or NT-proBNP

BNP or NT-proBNP

Ambulatory pts with new-onset dyspnea / NYHA class II-IV

At risk for HF

Other biomarkers of myocardial injury or fibrosis^*

BNP or NT-proBNP, and cardiac troponin (COR I)

End

BNP or NT-proBNP

^*Other biomarkers of injury or fibrosis include soluble ST2 receptor, galectin-3, and high-sensitivity troponin.

BNP or NT-proBNP

Predischarge BNPor NT-proBNP

Other biomarkers of myocardial injury or fibrosis^*