Various terms may be used to describe skin cancers involving different skin-cell types, which may demonstrate different characteristics. Non-melanoma skin cancers frequently develop in sun-exposed areas of the skin. The exact cause of melanoma is unclear, but over-exposure to UV radiation, including artificial tanning booth treatments, can be a serious risk factor. Melanoma has the potential to metastasize to any organ through the blood and lymphatic routes, including to the lungs and the brain.
Basal cell carcinoma commonly develops on sun-exposed areas, especially on the face. Initially, it may take the form of a small, smooth, translucent, pigmented papule or nodule, but it eventually becomes an ulcerative lesion.
Squamous cell carcinoma can be invasive. It may appear as a rough, scaly, and possibly inflamed or bleeding tumor. Exposed upper extremities and facial areas are common sites for such carcinomas.
Different types of malignant melanoma differ greatly in their clinical presentations and other aspects. In general, the ABCD mnemonic may be used as a reminder when assessing a suspected melanoma:
Sun exposure can cause degenerative changes in the skin. UVB radiation is believed to have carcinogenic effects, and ultraviolet-A (UVA) radiation adds to that effect. Many skin cancers are thought to be directly or indirectly induced by prolonged sun exposure, damage from which is cumulative in nature.