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Table 35.6

Sequential (Sepsis-Related) Organ Failure Assessment Score

Organ systemVariable (units)DysfunctionFailure
1234
Respiratory systemPaO2/FiO2 ratio (kPa)<53.3<40<26.7 and ventilation<13.3 and ventilation
Cardiovascular systemMAP (mmHg) or vasoactive drugs μgm/Kg/minMAP <70Dopamine <5 or Dobutamine

Epinephrine or

norepinephrine <0.1

Epinephrine or

norepinephrine >0.1

Central nervous systemGlasgow coma score13–1410–126–9<6
CoagulationPlatelets<150<100<50<20
Renal

Creatinine (μmol/L) OR

Urine output (mL/24 hr)

110–170171–299

300–440

<500 mLs/24 hours

>400

<200 hours

LiverBilirubin μmol/L30–3233–101102–204>204