Initial Antibiotic Therapy for Suspected Native Joint Septic Arthritis
Antibiotic therapy (IV, high dose) | ||
---|---|---|
Organisms on Gram stain | Not allergic to penicillin | Allergic to penicillin |
Gram-positive cocci | Vancomycin if MRSA suspected | Clindamycin |
Gram-negative cocci | Ceftriaxone | Ceftriaxone (mild allergy) Seek expert advice if severe allergy |
Gram-negative rods | Piperacillin-tazobactam | Ciprofloxacin |
None seen | Flucloxacillin Vancomycin if MRSA suspected | Clindamycin |