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Table 23.6

Causes of Plasma Aspartate and Alanine Transaminase Levels of More Than 1000 Units/L

Common

Less common or rare

  • Acute exacerbation of autoimmune chronic active hepatitis
  • Reactivation of chronic hepatitis B
  • Acute Budd-Chiari syndrome
  • Veno-occlusive disease
  • HELLP syndrome of pregnancy (haemolysis, elevated liver enzymes, low platelet count)
  • Acute fatty liver of pregnancy
  • Hepatic infarction (may complicate HELLP syndrome)
  • Hepatitis delta in a chronic carrier of hepatitis B
  • Acute Wilson disease
  • Massive lymphomatous infiltration of the liver
  • Parasitic biliary obstruction