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Table 95.1

Disorders Which May Be Mistaken for Cellulitis

DisorderDistinguishing features

Necrotizing fasciitis

Leg eczema (venous eczema or contact dermatitis) (NB cellulitis may complicate eczema)

Deep vein thrombosis (DVT) (NB cellulitis may complicate DVT)

Allergic reaction to insect sting or bite

Ill patient

Severe pain, disproportionate to physical signs

Skin may be very tender, with blue-black

discolouration and blistering

Rapid clinical progression

Longer history

May be bilateral (bilateral cellulitis is rare)

No fever or systemic symptoms

Itching rather than tenderness of the skin

History of varicose veins or DVT

Crusting or scaling (in cellulitis the skin is typically smooth and shiny)

Proximal margin of erythema usually not well demarcated

If clinical setting suggests DVT (Chapter 56), duplex scan of leg veins needed to exclude this

No ascending lymphangitis

Itching

DisorderDistinguishing features
Chronic oedema/Usually bilateral
lymphoedemaErythema may be feature
(NB cellulitis may complicate chronic oedema or lymphoedema)No fever
Gouty arthritisArthritis prominent
Typically involves first metatarsophalangeal joint (Chapter 97)
PyodermaRapidly enlarging painful ulcer
gangrenosumAssociated systemic disease (most often inflammatory bowel disease) in 50%